Schizophrenia
is a complex chronic mental disorder, which affects 24 million people worldwide
and is responsible for significant functional impairment. Several studies have
tried to understand this disease and the involvement of the central nervoussystem.
Neuro-imaging
studies have shown structural brain changes in schizophrenia, already evident
in the first psychotic episode. It is essential to realize how the
neurodevelopment and the neurodegenerative domains influence this disease. In
our manuscript, entitled "Evaluation of Structural Changes in the Retina
of Patients with Schizophrenia", we try to understand how a non-invasive
exam, as Optical Coherence Tomography (OCT), can also be useful in
schizophrenia, to evaluate the thickness of the retinal nerve fiber layer
(RNFL) and macular volume and thickness. In the second part of this study, we
try to realize the correlation of these data with cognitive functioning in
schizophrenic patients, abstract previously published (entitled “Correlation
between macular OCT and cognitive function in patients with schizophrenia”).
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